Broad-Spectrum Antimycotic with Fungicidal action for local application only.
The active substance in Canesten Clotrimazole Cream 1% w/w is clotrimazole. Clotrimazole belongs to a group of medicines called imidazoles. The primary mechanism of action of clotrimazole is against the division and growing of fungi. Clotrimazole alters the permeability of the fungal cell wall and inhibits the activity of enzymes within the cell. It specifically inhibits the biosynthesis of ergosterol required for cell membrane production.